Systems Medicine
“Systems Medicine” by Jane P.F. Bai, published by Springer US on April 19, 2022, is a comprehensive volume that delves into the latest technological advances in systems medicine, particularly in relation to precision medicine. This first edition spans 347 pages and is presented in English. The book is structured into four distinct parts, each addressing critical aspects such as biomarker identification, computational approaches in pharmaceutical research, and methodologies in network biology.
Readers will find detailed discussions on the integration of omics and phenotypic data, as well as insights into drug repurposing and patient response modeling. The chapters are designed to be accessible, featuring introductions to topics, lists of materials and reagents, and step-by-step laboratory protocols. This resource aims to facilitate collaboration within the scientific community, addressing both medical needs and educational requirements in the fields of biology, pharmacology, and medical research.
Official synopsis Publisher
This volume explores the latest technological advances and covers all facets of systems medicine with respect to precision medicine. The chapters in this book are organized into four parts. Part One highlights the recent achievements in proteomics for biomarkers identification, integration of omics and phenotypic data for precision medicine, and medicine-guided treatment of drug-induced Stevens-Johnson syndrome. Part Two covers systems-based computational approaches for pharmaceutical research and drug development, the principle of optimizing systemic exposure of drugs, and Animal Rule for drug repurposing. Part Three looks at computational tools and methodologies of network biology, quantitative systems toxicology, and modeling and stimulating patient response variabilities. Part Four talks about how systems medicine can address unmet medical and health needs, and identify educational needs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Systems Medicine: Methods and Protocols is a valuable resource for the scientific community that will help researchers work together toward the further advancement of achieving the goal of promoting global health.
Chapter 8 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
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