Myeloid-Derived Suppressor Cells
Myeloid-Derived Suppressor Cells by Sven Brandau, published by Springer US on November 26, 2020, is a comprehensive resource spanning 220 pages. This volume delves into various experimental approaches to investigate myeloid-derived suppressor cells (MDSC), providing insights into their characterization. The chapters cover a range of topics, including the study of MDSC in human patient samples and the use of advanced techniques such as flow cytometry and mass cytometry for immunophenotyping.
Readers will find detailed methodologies for functional characterization of MDSC through biochemical, immunological, and microscopy approaches, as well as high-resolution genomics and visualization techniques. Written in the established Methods in Molecular Biology series format, the book includes introductions to each topic, necessary materials and reagents, and step-by-step laboratory protocols. This edition serves as a valuable resource for both novices and experienced researchers in biology, medicine, and veterinary medicine, facilitating the exploration of new protocols and enhancing understanding of MDSC.
Official synopsis Publisher
This volume explores various experimental approaches that can be used to investigate myeloid-derived suppressor cells (MDSC) and can be useful to understand the characterization of these cells. The chapters in this book cover topics such as the study of MDSC in human patient samples; employing flow cytometry or magnetic enrichment; immunophenotyping using multi-parameter flow cytometry and mass cytometry; functional characterization of MDSC by biochemical, immunological, and microscopy approaches; MDSC characterization through the use of high-resolution genomics; and novel methods of high-resolution visualization of living tissue and the purification of granulocytes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Myeloid-Derived Suppressor Cells: Methods and Protocols is a valuable resource for novices in this field to help them start their research on MDSC, and experienced investigators looking to establish new protocols in their lab. This book is great for anyone working in the field of biology, medicine, and veterinary medicine.
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