Cryopreservation Current Advances and Evaluations
Cryopreservation Current Advances and Evaluations by Marian Quain, published by BoD – Books on Demand on June 10, 2020, offers a detailed exploration of the storage of biological cells at subzero temperatures while maintaining their functionality. This 190-page book addresses the complexities and challenges associated with cryopreservation, including the effects of cooling and thawing on organisms and their metabolic systems.
Readers will find comprehensive information on the role of cryoprotectant agents (CPAs) in preventing ice formation during the preservation process. The book delves into the potential toxicity of CPAs at high concentrations and emphasizes the need for further research to understand their mechanisms of action. Additionally, it discusses the development of new CPAs that could enhance the preservation of cells, tissues, and organs without compromising their biological integrity.
Official synopsis Publisher
Cryopreservation – Current Advances and Evaluations sheds light on storage of cells at subzero temperatures while ensuring that biological functionality is not compromised. Cryopreservation presents a perfect technique by which life can be preserved for posterity. However, there are many challenges to overcome and questions to answer, such as: Are organisms and metabolic systems functioning normally after cooling and thawing? This book provides comprehensive information on cryopreservation with a particular focus on cryoprotectant agents (CPAs). CPAs prevent ice from forming on cryogenically preserved cells, tissues, and organs, but can become toxic at high concentrations. As such, more research is needed to determine their precise mechanisms of action and to develop potential new CPAs that will not compromise the biology of cells. This book is an attempt in this direction.
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