Correcting the Code Inventing the Genetic Cure for the Human Body

Correcting the Code Inventing the Genetic Cure for the Human Body by Larry Thompson, published by Simon & Schuster in 1994, offers an insightful exploration into the groundbreaking advancements in genetic therapy. This first edition spans 378 pages and is presented in English. The book chronicles the pivotal moment when Dr. French Anderson and his team at the National Institutes of Health injected a young girl with genetically altered white blood cells, marking the dawn of human gene therapy and the potential for molecular cures for various diseases.
Readers will discover the intricate journey of researchers who sought to overcome significant barriers in medicine by repairing human genes responsible for illnesses. The narrative delves into the historical context of genetic science, detailing the evolution of ideas surrounding DNA and the ethical challenges posed by genetic engineering. Thompson effectively demystifies complex scientific concepts, making them accessible to a general audience while highlighting the dedication of key figures in the field. This account captures the dynamic interplay of innovation, setbacks, and the relentless pursuit of breakthroughs in genetics and genomics.
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“When Dr. French Anderson, researcher and physician at the National Institutes of Health, assembled the team that injected a young girl from the suburbs of Cleveland with a special solution of white blood cells, he ushered in a brave new world of science and medicine. Those cells were genetically altered – or corrected – to produce a critical enzyme necessary to create a fully functioning immune system, which his young patient was born without. The age of human gene therapy had arrived. Along with it will come the molecular cures for cancers and heretofore incurable conditions such as cystic fibrosis, perhaps even AIDS.” “Correcting the Code is the eminently readable and remarkable story of the handful of doctors and researchers who deeply believed they could break one of the last barriers in medicine: repairing human genes that cause illnesses. Even before Watson and Crick successfully modeled DNA, the idea of changing the genetic composition of humans had long been a scientific Holy Grail – despite the stain of eugenics and the public phobia of genetic engineering gone amok. Over the last twenty years, as the pace of research has accelerated, laboratories have entered a sort of race to claim the final breakthrough, to be the first to successfully treat a human patient. The story of that frenzied research contains the great scientific upheavals in the field of biology, including a new understanding of how specific molecules interact to compose living cells that make up the human body.” “This is the riveting account of how a great scientific puzzle – finding a way to repair actual human molecules – was solved, of the intellectual and political milieu in which it occurred, and of the remarkable people who committed their lives to the task – Anderson, Michael Blaese, Ken Culver, Richard Mulligan, and others.” “Author Larry Thompson makes the seemingly indecipherable world of genetic science understandable to the general reader. Furthermore, he unravels a dramatic story of inspired invention, frustrating dead ends, the clash of egos, the fits and starts of innovation that reveal how science is conducted in the real world.”–BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
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