Crick A Mind in Motion

Crick A Mind in Motion by Matthew Cobb, published by Basic Books on November 11, 2025, is a comprehensive biography that explores the life of Francis Crick, co-discoverer of DNA’s structure and a pioneering neuroscientist. This 608-page work delves into the significant moments that shaped Crick’s life and career, highlighting not only his scientific achievements but also the personal encounters that influenced his character and aspirations.
In this biography, readers will find an in-depth examination of Crick’s journey, from his famous collaboration with James Watson to the philosophical reflections that guided his scientific pursuits. Cobb presents a nuanced portrait of Crick, revealing both his triumphs and challenges as he sought to uncover the mysteries of existence. The book addresses themes related to the history and philosophy of science, as well as the biological sciences, offering insights into the mind of one of the 20th century’s most influential figures.
Official synopsis Publisher
A “thrilling biography of one of the 20th century’s greatest minds” (David Eagleman): Francis Crick, codiscoverer of the structure of DNA, pioneering neuroscientist, and audacious genius
What are the moments that make a life? In Francis Crick’s, the decisive moment came in 1951, when he first met James Watson. Their ensuing discovery of the structure of DNA made Crick world-famous. But neither that chance meeting nor that discovery made Crick who he was.
As Matthew Cobb shows in Crick, it is another chance encounter, with a line from the writing of Beat poet Michael McClure, that reveals Crick’s character: “THIS IS THE POWERFUL KNOWLEDGE,” it shouted. Crick, having read it, would keep it with him for the rest of his life, a token of his desire to solve the riddles of existence. John Keats once accused scientists of merely wanting to “unweave a rainbow,” but it was an irrepressible, Romantic urge to wonder that defined Crick, as much as a desire to find the basis of life in DNA and the workings of our minds.
For the first time ever, Cobb presents the full portrait of Crick, a scientist and a man: his triumphs and failings, insights and oversights. Crick set out to find the powerful knowledge. Almost miraculously, he did.
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