Hi-C Data Analysis Methods and Protocols

Hi-C Data Analysis Methods and Protocols by Silvio Bicciato, published by Springer US on August 21, 2021, is a comprehensive resource consisting of 354 pages in English. This volume presents a detailed set of methods and tools for processing, analyzing, and interpreting Hi-C data, addressing various biological problems through state-of-the-art computational procedures.
Readers will find a structured approach to the applications of Hi-C, with chapters that include introductions to topics, necessary materials and reagents, and step-by-step laboratory protocols. The book also offers troubleshooting tips and insights into avoiding common pitfalls, making it a valuable guide for computational and molecular biologists focused on chromatin 3D architecture and transcription regulation.
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This volume details a comprehensive set of methods and tools for Hi-C data processing, analysis, and interpretation. Chapters cover applications of Hi-C to address a variety of biological problems, with a specific focus on state-of-the-art computational procedures adopted for the data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Hi-C Data Analysis: Methods and Protocols aims to help computational and molecular biologists working in the field of chromatin 3D architecture and transcription regulation.
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