The Intestine
The Intestine by Ahmed El-Hashash, published by Elsevier Science on June 18, 2021, is a comprehensive exploration of recent advancements in stem cell research related to intestinal health. This edition, comprising 204 pages, delves into innovative in vitro and in vivo research tools that have been developed to investigate stem cell biology and their potential applications in treating intestinal diseases. The book presents a detailed overview of methodologies such as organoid cultures and genetic editing, providing a scientific foundation for understanding the role of stem cells in the intestine.
Readers will find a thorough examination of the current state of stem cell research, including insights into human and murine organoid cultures and the use of human induced pluripotent stem cells (iPSCs) to model intestinal diseases. The text is divided into two major sections that focus on understanding stem cell functions and the development of methods to translate these findings into clinical applications. This volume addresses the challenges and opportunities presented by cutting-edge technologies in regenerative medicine, emphasizing the real-world implications of stem cell therapies for intestinal disorders.
Official synopsis Publisher
The intestine is among the leading organs, in which several cutting edge in vitro and in vivo research tools and approaches have recently been developed and used to investigate stem cell biology/function, and the potential applications of stem cells in the treatment of intestinal diseases. These cutting-edge research tools and approaches involve human and murine organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases.
Stem Cell Innovation in Health and Disease: Volume 1: The Intestine contains two major sections describing cutting edge research for understanding stem cell functions in the intestine, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model intestinal diseases, through the cutting-edge research, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of intestinal diseases/disorders. This volume, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the intestine in the real world.
- Provides intensive scientific background and most recent information on cutting edge research to understand intestinal stem cell functions and develop methods to bring stem cells from bench to bedside for different intestinal diseases
- Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and the CRISPR gene editing system in the intestine
- Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the intestine
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