Measuring Cell Mechanics
Measuring Cell Mechanics by Margaret Gardel, published by Morgan & Claypool Life Sciences in 2015, is a concise exploration of the mechanical properties of cells. This 74-page edition, written in English, introduces readers to the primary tools used to measure mechanical interactions and material properties within cells. The book emphasizes how cells interact with their external environment and generate internal forces, providing a foundational understanding of these dynamics.
Readers will find a detailed examination of techniques applicable at both molecular and cellular scales, focusing on methods that actively and passively probe mechanical systems. The text covers fundamental principles, relevant length and timescales, and typical measurement magnitudes, while also highlighting recent applications in quantitative cell biology research. This work serves as a valuable resource for those interested in the intersection of science, life sciences, and molecular biology, shedding light on the regulatory roles of mechanical interactions in various physiological processes.
Official synopsis Publisher
Cells are inherently physical entities that both experience mechanical forces from their external environment and generate their own internal forces to drive cell motion. Our particular aim here is to present the reader with an introduction to the primary tools used to measure these mechanical interactions and the material properties of cells that result from them. These approaches can be applied to a diverse array of physiological processes and systems, providing important insight into the regulatory roles of mechanical interactions in cells. We cover techniques at both the molecular and cellular scales, including those that actively and passively probe the system. Along the way we cover the fundamental principles of each approach, while emphasizing the relevant length and timescales, along with the typical magnitudes of the measurements that can be made. Each section ends by highlighting uses of the various techniques in recent relevant publications, illustrating the exciting future of cell mechanics in quantitative cell biology research.
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